HCG During Or After Testosterone Replacement Therapy

Your body does more than just act as a male sex hormone. It is a key player in modulating many body functions, including cognitive ability and mood as well as muscle mass and production sperm. Hypogonadism (also known as low testosterone) is a common problem among men of all ages. It is also known that it can affect fertility and testicular sizes. This is where Testosterone Replacement Therapy comes into play.

What happens if you have low testosterone?

Your body’s testosterone levels begin to decrease as you reach your 40s and 50s. Low testosterone levels can cause the following symptoms:

  • Testicle shrinkage
  • Erectile dysfunction/impotence
  • Reduced muscle strength and mass
  • Motivational issues
  • Weaker and more spontaneous erections
  • Stamina reduced
  • Concentration problems
  • Depression and sadness
  • Reduce sperm count

Although testosterone replacement therapy can be effective in increasing natural testosterone levels, it has negative effects on fertility, sperm count and testicle sizes. HCG can be used during or after TRT to treat testosterone depletion and preserve fertility, sperm count and other bodily functions.

What is Human Chorionic Gonadotropin?

Human Chorionic Gonadotropin is an essential hormone in maintaining pregnancy. It helps maintain pregnancy by supporting the ovarian corpus luteum. It would be reasonable to ask what HCG does for males.Testosterone Replacement Therapy

HCG is an analog of LH and serves to mimic the male role. LH is responsible in males for testosterone production and secretion. HCG stimulates ovulation in women and increases natural testosterone and sperm output from the testes in men. It was FDA-approved for use in treating fertility problems in females. HCG can also be used to treat hypogonadism (low-T) in males.
To increase testosterone levels in hypogonadal men, HCG is commonly used with or after testosterone replacement therapy. TRT reduces the production of eggs and shrinks the size of Leydig cells. HCG is used. HCG therapy preserves sperm production by maintaining intra-testicular testosterone levels. This will result in increased sperm production, fertility, and less testicle shrinkage.

How does HCG boost testosterone levels?

Hypogonadism (aka low testosterone levels) can increase your chances of infertility.
During hormone replacement therapy (TRT), the production of gonadotropin-releasing hormone (GnRH) from the hypothalamus stimulates the pituitary gland to stop releasing LH. The testicles’ volume and size decreases due to a lower level of LH.

Here is where HCG comes in. Supplemented with TRT HCG stimulates the testicles and continuously produces testosterone. This increases testosterone levels without causing hypogonadism. Testicles increase in size as a result of HCG.

What does the research say?

A 2019 study found that HCG treatment is safe and effective for hypogonadism symptoms in men. HCG increased their testosterone levels to over 300 ng/dL.
Another study found that HCG increased testosterone levels in older men with partial hypogonadism.

Additional benefits of HCG

Other than restoring sperm production, and increasing testosterone levels HCG also has these benefits:

  • You must maintain your testicular size.
  • Regulation of testosterone production
  • Enhancing sexual function is possible because testosterone levels are strongly associated with male sexuality.
  • Recovery from a condition or disease that lowers your testosterone levels.
  • Side effects of steroids on bodybuilders such as infertility or gonad shrinkage can be reversed.
  • Weight loss assistance
  • Correction of undescended testicles

How to take HCG

Because injectable HCG is more reliable, it should be used as such. HCG drops or supplements should not be used to replace medical-grade HCG. HCG injections can be administered using a small insulin needle in the lower stomach. This is to inject the hormone into the fat tissue or outer glute.

Are there any side effects to HCG?

Most men tolerate HCG well. It is rare for men to experience side effects. HCG side effects include:

  • Nausea
  • Vomiting
  • Skin rashes
  • Headaches
  • Redness, pain, swelling and inflammation at the injection site.
  • Stomach pain
  • Gynecomastia is a condition that causes breast enlargement in men.

In rare cases, HCG can cause severe allergic reactions such as anaphylactic reactions or mild skin rashes. Another rare side effect of HCG is blood clotting.


TRT (testosterone replacement therapy) is a great option to increase testosterone levels. Supplementing HCG with TRT increases intra-testicular testosterone, preserves sperm counts and boosts fertility. Other benefits include weight loss, increased sexual desire, and maintaining the size of testicle.
The American Urological Association states HCG is suitable for hypogonadal men on TRT who wish to maintain fertility. The literature has a lot of information on how HCG can maintain fertility while you are on TRT.
HCG increases testosterone levels by mimicking LH’s function. HCG can also be used to increase fertility in men with low sperm count or low testosterone.
Hypogonadotropic hypogonadism is a condition in which males are unable to produce sex hormones. HCG has been shown to increase sperm count in men suffering from HH by 25%. This helps them to conceive.
Another study found that testosterone replacement therapy (TRT), which is combined with HCG, increased sperm counts in men.
A 2018 study found that hypogonadism patients were able to retain their fertility using HCG. This helped them increase sperm production. 

Contact Domestic Peptides

If you have questions about taking a drug containing peptides, ask your doctor or feel free to reach out to Domestic Peptides, the best place to buy peptides. Domestic Peptides offers the best pricing on USA peptides online with a massive inventory containing DMAA, Cabergoline, MK677, and more are ready to ship right away. WARNING: This product is a very potent chemical. This product is NOT for human use and can be harmful if ingested. This product is for research/laboratory use only. This product is NOT in a sterile solution and is NOT to be injected. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and should not be misbranded, misused or mislabeled as a drug, food or cosmetic.