Enclomiphene Citrate 25mg per ml 30ml
Enclomiphene Citrate is a non-steroidal estrogen receptor antagonist that promotes gonadotropin-dependent testosterone secretion by the testes. The trans-stereoisomer to clomiphene citrate is enclomiphene.
Enclomiphene has antagonistic effects that can increase serum testosterone in men with secondary hypogonadism. It restores physiological endogenous testosterone production while maintaining testicular volume, and possibly spermatogenesis. Enclomiphene has shown significant effectiveness in physiologically restoring testosterone levels in secondary hypogonadism males in clinical trials.
Unexpectedly, the compound had a positive effect on fasting blood glucose. This result was accompanied by rapid accumulation of evidence from other researchers for a bidirectional association between low serum testosterone (syndrome 1) and obesity/metabolic disorder (syndromeX) in men.
The safety data from enclomiphene in short-term clinical trials have been comparable to those for testosterone gels or placebo. Enclomiphene is promising in treating secondary hypogonadism due to obesity, metabolic syndrome, and possibly infertility. These indications should be randomized placebo-controlled clinical trials.
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